ANXIETY AND DEPRESSION IN INDIVIDUALS WITH DRUG RESISTANCE EPILEPSYName : Dr. RM. Bhoopathy
Affliation : Professor
University : The Tamil Nadu Dr. M.G.R Medical University
Country : India
To study anxiety and depression in 506 with Drug resistant epilepsy
2850 epileptic patients in our epilepsy clinic between 2012 & 2014, were screened using Drug resistant epilepsy (ILAE,2010) criteria. 506 participants (age range 10-70 Years) who fulfilled the criteria underwent detailed clinical history, Neurological examination, EEG, MRI brain and neuropsychological assessment. Anxiety and depression were assessed using multiphasic questionnaire. Prior to assessment of anxiety and depression I. Q assessment was carried out using Weschlers intelligence scales. 147 participants (29.05%) who had mental retardation were excluded from administration of anxiety and depression scale
Out of 506, 31.82% (n=161) of them had anxiety and 28.06% (n=142) had depression, mixed anxiety and depression symptoms were observed in 24.9% (n=126). Chi square test showed significant association of Mesial temporal Sclerosis (MTS) with anxiety and depression. Also factors like early age of seizure onset, polytherapy, longer duration of seizure was associated with anxiety and depression (P<0.01).
Higher percentage of individuals with Drug resistant epilepsy often present with anxiety and depression when compared to other studies in persons with epilepsy. MTS is often associated with anxiety and depression in Drug resistant epilepsy. Early age onset of seizure, polytherapy, longer duration of seizure are also additional causes for anxiety and depression in intractable epilepsy patients.