Despite recent advances in acute stroke management, many stroke patients suffer from long-term disability. Most stroke patients regain their function partially or fully during the first 3 to 6 months depending on many factors; pre-stroke, stroke and post-stroke factors. Brain plasticity plays a major role in during stroke recovery, and motor-relearning and brain plasticity share the common mechanism. Successful neurorehabilitation is to drive beneficial plastic change and therefore to gain functional recovery. Ongoing improvements in the acute treatment of cerebrovascular diseases and organization of stroke services, many stroke survivors are in need of neurorehabilitation, as more than two-thirds show persisting neurologic deficits. While early elements of neurorehabilitation are already taking place on the stroke unit, after the acute treatment, the patient with relevant neurologic deficits usually takes part in an organized inpatient multidisciplinary rehabilitation program and eventually continues with therapies in an ambulatory setting afterward. Neuro-rehabilitation (physical therapy, occupational therapy, etc.) helps hemiparetic stroke patients confronted with a loss of motor skills on one side of their body, to recover some of their motor functions after a cerebrovascular accident. Stroke rehabilitation is a progressive, dynamic, goal orientated process aimed at enabling a person with impairment to reach their optimal physical, cognitive, emotional, communicative and/or social functional level.